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Orientation to Pharmacology
Chapter 1 Orientation to Pharmacology Copyright (c) Elsevier Inc. All rights reserved.
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Orientation to Pharmacology
Define the following terms Drug Pharmacology Clinical pharmacology Pharmacotherapeutics Copyright (c) Elsevier Inc. All rights reserved.
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Properties of an Ideal Drug
Effectiveness Safety Selectivity Reversible action Predictability Ease of administration Minimal drug interactions Low cost Chemical stability Possession of a simple generic name
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Intensity of Drug Responses
Multiple factors influencing drug response are Administration Pharmacokinetics Pharmacodynamics Individual variations
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Pharmacokinetics The four major pharmacokinetic processes are
Drug absorption Drug distribution Drug metabolism Drug excretion
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Pharmacodynamics The impact of drugs on the body once a day has
reached its site of action
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Therapeutic Objective
Drug therapy should provide maximal benefit with minimal harm
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