1. Specificity of production of reactive oxygen species (ROS) against Aspergillus fumigatus conidia by phagocytes from healthy and CF donors.
Specificity of production of reactive oxygen species (ROS) against Aspergillus fumigatus conidia by phagocytes from healthy and CF donors. Polymorphonuclear cells (PMN) (a) (2.5×106 per mL) and peripheral blood mononuclear cells (PBMC) (b) (2.5×106 per mL) were stimulated with A. fumigatus conidia (5×107 per mL), 2 µm latex beads (5×107 per mL), depleted zymosan (200 µg·mL–1) and lipopolysaccharide (LPS) (50 ng·mL–1). Total ROS production is shown as the area under the curve (AUC) over 2 h (mean±sem) for five healthy and three CF donors. *: p<0.05 (Mann–Whitney U-test).
Shan F. Brunel et al. ERJ Open Res 2018;4:
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