1. Median NT-proBNP levels (pg/mL) by GFR and 60-day survival
Admission GFR
Dead by 60 d
Alive at 60 d p
<60 mL/min/1.73m2
5565
2528
0.001
>60 mL/min/1.73m2
1423
163
<0.001
NT-proBNP=N-terminal brain-type natriuretic peptide
GFR=glomerular filtration rate
Anwaruddin S et al. J Am Coll Cardiol 2005; available at

2. Sensitivity and specificity for diagnosing HF, by NT-proBNP cut points and renal function
Parameter
GFR <60 mL/min/1.73 m2
GFR >60 mL/min/1.73 m2 (age >50 y)
GFR >60 mL/min/1.73 m2 (age <50 y)
Cut point (pg/mL)
>1200
>900
>450
Sensitivity (%) 89 85
Specificity (%) 72 88
NT-proBNP=N-terminal brain-type natriuretic peptide
GFR=glomerular filtration rate
Anwaruddin S et al. J Am Coll Cardiol 2005; available at