1. Can Primary Care Physicians Take the Lead in Combating Obesity?

3. Introduction/Background

4. Why Obesity Is a Disease

5. Obesity Is a Chronic Condition: A Disease

6. Mechanisms of Food Intake Regulation

7. The Obesogenic Environment

8. Medical Complications of Obesity

9. Post-Hoc Analysis Look AHEAD: The Importance of ≥ 10% Weight Loss

10. The Primary Care Physician Is Ideally Placed to Engage the Person With Obesity

11. How Much Does the Patient Need to Know About the Pathophysiology of Obesity?

12. Obesity Treatment Success: % Body Weight Lost

13. Available Weight-Loss Agents

14. Orlistat-Induced Weight Loss and Maintenance at 1 Year

15. Percentage Weight Loss From Baseline for the Modified ITT-LOCF Population and the Completer Population: Naltrexone + Bupropion vs Placebo

16. SCALE: Change in Body Weight (%), Liraglutide vs Placebo

17. When to Refer the Patient to a Specialist

18. Summary and Conclusions

19. Abbreviations

20. Abbreviations (cont)