1. Pathways to Quit: Options for Smoking Cessation Strategies

3. Smoking: The Size of the Problem

4. Smoking Leads to 11-Year Loss of Lifespan

5. Ingredients of Cigarettes

6. Smoking Reduction

7. Smoking Reduction ≠ Harm Reduction

8. Cutting Down Does Not Significantly Reduce Mortality Compared With Heavy Smoking

9. A Classic Approach in the Clinic

10. Lack of Readiness

11. Effectiveness of Monotherapies

12. NRT: Other Options

13. How Does Varenicline Work?

14. EAGLES Trial Design

15. EAGLES Trial: Reported Neuropsychiatric Adverse Events

16. Efficacy: CARs in the Nonpsychiatric and Psychiatric Cohorts

17. Smokers Not Ready to Make an Abrupt Quit Attempt

18. The Challenge of Making a Quit Attempt

19. Increasing Quit Attempt Acceptability: The Flexible Quit Date Paradigm

20. Efficacy of a Flexible Quit Date vs an a Priori Quit Date Approach to Smoking Cessation: A Cross-Study Analysis

21. Increasing Quit Attempt Acceptability: The Flexible Quit Date Paradigm

22. Smoking Reduction With the Goal of Quitting

23. There Is No Safe Level of Smoking

24. Smokers Not Ready to Make an Abrupt Quit Attempt

25. Prompting Quit Attempts in Smokers Not Currently Trying to Quit

26. Example of Smoking Cessation Plan

27. Combined Pharmacotherapy and Behavioral Interventions for Smoking Cessation

28. Smoking Cessation in Preventive Cardiology Clinic

29. Benefits of Smoking Cessation

30. Statistics on NHS Stop Smoking Services

31. Very Brief Advice

32. Very Brief Advice (cont)

33. Effectiveness of Monotherapies

34. Association Between E-Cigarettes and Smoking Cessation

35. Conclusion