1. Immune System Project : CD28
BY: Wells Powell
&
Tamia Johnson

2. CD28: Resting and Activation of a T-cell CD28 T-cells appear relatively, through A variety of mechanisms significantly impacting, And significantly contributing, to the immune Defect, that is characterized of the elderly Frequently, expanded and constrained, to the Adaptive immune system by completing for Available space, IN THIS PLACE!!!

3. What Is it!!!!
CD28 signaling promotes T cell activation and upregulation of CTLA-4. Blockade of CD28 signal with CTLA-4 I or B7 antibodies inhibits T cell activation. CTLA-4 signaling down-regulates T cell responses. Inhibition of this signal with anti-CTLA-4 maintains an active immune responses. Resting T cells express TCR and CD28; activated T cells express CD28, CTLA-4, and TCR; and APCs express MHC plus peptide and B7.

6. Disease related to it! Diseases have been found through this cell
Among various inflammatory syndromes
Including HIV wells
And chronic disease in these windows
Disease related to it!