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Volume 116, Issue 1, Pages (January 1999)

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Presentation on theme: "Volume 116, Issue 1, Pages (January 1999)"— Presentation transcript:

1 Volume 116, Issue 1, Pages 54-57 (January 1999)
Prevalence of the I1307K APC gene variant in Israeli Jews of differing ethnic origin and risk for colorectal cancer  Paul Rozen*,‡, Ruth Shomrat§, Hana Strul*,‡, Tova Naiman§, Nataly Karminsky∥, Cyril Legum§,‡, Avi Orr-Urtreger§,‡  Gastroenterology  Volume 116, Issue 1, Pages (January 1999) DOI: /S (99) Copyright © 1999 American Gastroenterological Association Terms and Conditions

2 Fig. 1 Methods used for identification of the I1307K variant: (A and B) by ASO; (C) by APC-Pronto-Gamidagen kit; and (D) by DNA sequencing. (A) Hybridization with the normal ASO primer. (B) Hybridization with the mutant ASO primer. Dark arrows designate mutant control, open circles water control. (C) Each line was hybridized with either normal (N) or mutant (M) allele. (D) Gray arrows designate T to A polymorphism. Samples 2 and N were normal. Samples 1 and 09 were mutants, the mutant sample 09 is shown in all 3 methods. Gastroenterology  , 54-57DOI: ( /S (99) ) Copyright © 1999 American Gastroenterological Association Terms and Conditions


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