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Treating Flu with Skin of Frog

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1 Treating Flu with Skin of Frog
James E. Crowe  Immunity  Volume 46, Issue 4, Pages (April 2017) DOI: /j.immuni Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Identification of Urumin Peptide and Antiviral Activity
Top panel: Skin secretions were collected from wild-caught South Indian frogs following mild electrical stimulation. DNA copies of expressed genes in skin secretions were sequenced and used for expression of short synthetic peptides. Bottom panel: Synthetic peptides were tested for antiviral activity against influenza type A H1 subtype viruses in cell culture and in mice. The 27-amino acid peptide urumin exhibited micromolar activity against influenza, but minimal toxicity in a red blood cell assay. Immunity  , DOI: ( /j.immuni ) Copyright © 2017 Elsevier Inc. Terms and Conditions

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