1. Comorbidities, Fragility, and Quality of Life in Heart Failure Patients With Midrange Ejection Fraction 
Paloma Gastelurrutia, PhD, Josep Lupón, MD, PhD, Pedro Moliner, MD, Xiaobo Yang, MB, German Cediel, MD, PhD, Marta de Antonio, MD, PhD, Mar Domingo, MD, PhD, Salvador Altimir, MD, Beatriz González, CN, Margarita Rodríguez, CN, Carmen Rivas, CN, Violeta Díaz, CN, Erik Fung, MB, ChB, PhD, Elisabet Zamora, MD, PhD, Javier Santesmases, MD, Julio Núñez, MD, PhD, Jean Woo, MD, Antoni Bayes-Genis, MD, PhD, FESC 
Mayo Clinic Proceedings: Innovations, Quality & Outcomes  
Volume 2, Issue 2, Pages (June 2018)
DOI: /j.mayocpiqo
Copyright © 2018 Mayo Foundation for Medical Education and Research Terms and Conditions

2. Figure 1
The prevalence of each component of fragility based on the prespecified definition according to the LVEF subgroup. P values between HFrEF and HFmrEF and between HFmrEF and HFpEF. GDS = Geriatric Depression Scale; LVEF = left ventricular ejection fraction; HFmrEF = heart failure and mildly reduced ejection fraction; HFpEF = heart failure and preserved ejection fraction; HFrEF = heart failure and reduced ejection fraction; OARS = Older Americans Resources and Services.
Mayo Clinic Proceedings: Innovations, Quality & Outcomes  2018 2, DOI: ( /j.mayocpiqo )
Copyright © 2018 Mayo Foundation for Medical Education and Research Terms and Conditions

3. Figure 2
Adjusted cumulative incidence curves up to 11 years for the composite end point in patients with HFmrEF according to the presence of (A) fragility, (B) the number of comorbidities, and (C) the MLHFQ score (divided into quartiles). Age, sex, and NYHA functional class III/IV were included as covariates in the model. HFmrEF = heart failure and mildly reduced ejection fraction; MLHFQ = Minnesota Living with Heart Failure Questionnaire; NYHA = New York Heart Association; QOL = quality of life.
Mayo Clinic Proceedings: Innovations, Quality & Outcomes  2018 2, DOI: ( /j.mayocpiqo )
Copyright © 2018 Mayo Foundation for Medical Education and Research Terms and Conditions