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Published byElmar Baum Modified over 6 years ago
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Effects of bretylium or 6-OHDA on action potential-evoked Ca2+ transients in axon bundles and varicose nerve terminals in mouse vas deferens
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Bretylium-resistant varicosities Mouse vas deferens
Action potential-evoked calcium transients in strings of varicosities not blocked by bretylium (20 µM; 2 hours) Double click on picture to replay the movie
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Bretylium-sensitive varicosities
Action potential-evoked calcium transients in a string of varicosities blocked by bretylium (20 µM; 2 hours; left panel and, reversed by amphetamine (right panel). Arrows point to the string of bretylium-sensitive/amphetamine-sensitive varicosities. Double click on picture to replay the movie
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Lack of effect of 6-OHDA on Ca2+ transients in
preterminal axon bundles Single pulse 10 pulses at 10 Hz Note the vigorous contraction in the right hand panel Double click on picture to replay the movie
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