1. "No one can make you feel inferior without your consent."
11/23/2018
Title: Biology 3/14/07
Objectives:
To learn about the historical discoveries surrounding the genetic material, DNA.
Class Topics
Hand in W.S. Tuning in to radioisotopes
Check Grade Sheets
Review Chapter 9 Quiz 1
Review DNA structure & Photo 51
Notes – Chapter 9
"No one can make you feel inferior without your consent."
Eleanor Roosevelt
Friday, November 23, :20 AM

2. Class Assignments W.S. Tuning in to Radioisotopes 3/14/07
11/23/2018
Class Assignments
What
By When
W.S. Tuning in to Radioisotopes 3/14/07
Read /14/07
W.S /16/07
Doublin’ DNA 3/16/07
Due this class period
Due next class period
Due in the future

3. 11/23/2018
Grade Sheet
2A – p. 157 (5 pts.)

4. Rosalind Franklin 1951 - X-ray diffraction Maurice Wilkins
11/23/2018
Rosalind Franklin
X-ray diffraction
Maurice Wilkins
Suggested that DNA was two strands
Tightly coiled helix
Photo 51, flash

5. From: http://www.pbs.org/wgbh/nova/photo51/pict-01.html
11/23/2018
From:

6. 11/23/2018
James Watson (American) and Francis Crick (British) discovered the shape and organization of DNA
Double helix
two strands
sugar/phosphate backbone
nitrogenous bases in middle
Won Nobel Prize for DNA model
with Maurice Wilkins
Watson and Crick

7. 11/23/2018

8. 11/23/2018
DNA double helix (like a spiral staircase) is easily replicated (doubled)
Occurs during S phase of cell cycle
1. Enzyme, DNA helicase, attaches to DNA molecule
Hydrogen bonds between strands break (DNA unzips and unwinds)
Forms replication forks
Areas where the strands separate
Replication (PBS)

9. 11/23/2018
2. DNA polymerase bonds free nucleotides (floating in nucleus) to exposed nitrogen bases
adenine to thymine & guanine to cytosine
3. Hydrogen bonds formed between nitrogen bases
Proofreading
DNA polymerase can go back and check for errors
1 error per 1 billion nucleotides
Replication (DNAi)

10. 11/23/2018

11. Lab – Doublin’ DNA Procedure 1 and 2 – cut out the nucleotides
11/23/2018
Lab – Doublin’ DNA
Procedure 1 and 2 – cut out the nucleotides
3. Use the DNA strand
GTCAACTG
4. Have work checked after #4
Pick up your homework W.S. when done.