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Definitions: Seizure, Epilepsy, Epilepsy Syndrome

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Presentation on theme: "Definitions: Seizure, Epilepsy, Epilepsy Syndrome"— Presentation transcript:

1

2 Definitions: Seizure, Epilepsy, Epilepsy Syndrome

3 Goals of Medical Therapy

4 Individualizing AED Selection

5 Comorbidities

6 AED Mechanisms of Action

7 Effectiveness of AED Combination Therapy Based on Mechanism of Action

8 Effectiveness of AED Combination Therapy Based on Mechanism of Action (cont)

9 Newest AEDs for Partial-Onset Seizures

10 Clobazam: Indication

11 Clobazam: MOA and Pharmacokinetics

12 Clobazam: Clinical Efficacy

13 Clobazam: Adverse Effects

14 Clobazam: Drug Interactions

15 Clobazam: Summary/Dosing

16 Eslicarbazepine Acetate: Indication/ MOA

17 Eslicarbazepine: Pharmacokinetics

18 Eslicarbazepine: Clinical Efficacy

19 Eslicarbazepine: Efficacy (cont)

20 Eslicarbazepine: Adverse Effects

21 Eslicarbazepine: Drug Interactions/Dosing

22 Ezogabine: Indication/MOA

23 Ezogabine: Pharmacokinetics

24 Ezogabine: Clinical Efficacy

25 Ezogabine: Adverse Effects

26 Ezogabine: Adverse Effects (cont)

27 Ezogabine: Dosing

28 Perampanel: Indication/MOA

29 Perampanel: Pharmacokinetics

30 Perampanel: Clinical Efficacy

31 Perampanel: Pooled Analysis of 3 Phase 3 Studies

32 Perampanel: Adverse Effects

33 Perampanel: Drug Interactions

34 Perampanel: Dosing

35 Perampanel: Dosing (cont)

36 Abbreviations

37 Abbreviations (cont)

38 References

39 References (cont)

40 References (cont)

41 References (cont)


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