1. Meta-analysis of randomised controlled trials
Peter M Rothwell, Gary Robertson 
The Lancet 
Volume 350, Issue 9085, Pages (October 1997)
DOI: /S (05)
Copyright © 1997 Elsevier Ltd Terms and Conditions

2. Figure
Comparison of estimate of relative treatment effect derived from meta-analysis of early trials (years 1 and 2) with point estimate of treatment effect derived from meta-analysis of subsequent trials in random selection of 26 published meta-analyses
Points lying below diagonal line represent overestimation of relative treatment effect by early trials compared with subsequent trials. OR=odds ratio.
The Lancet  , DOI: ( /S (05) )
Copyright © 1997 Elsevier Ltd Terms and Conditions