1. The Immune System
Medical Foundations

2. Topic Outline 1st and 2nd lines of Defense The Immune System innate
B cells
Vaccinations
T cells
Allergies
innate
acquired

3. First Lines of Defense:. Skin. Mucus membranes
First Lines of Defense: Skin Mucus membranes Chemical/enzymatic barriers
Chemical Barriers
Examples: Lysozymes & HCL

4. Second Lines of Defense include…
Inflammation
Pyrogenics (Fever)
Interferons
Complement system
And next page

6. Third Line of Defense: The Immune System
Our immune system is housed in our WBCs
WBCs = white blood cells=
Leukocytes
Lymphocytes
Phagocytes
Monocytes
Eosinophils

7. Two types of Lymphocytes
1. B Cells
2. T Cells
Antibody Defense= humoral
Cell to cell contact= cell mediated
Cytotoxic T cells
Helper T cells
To be discussed

8. Where we come from…
T lymphocytes
B lymphocytes

9. Onto: The Defense System of a B lymphocytes

10. Invaders and defenders
Antigens
Antibody
Foreign invaders

11. 5 general classes of immunoglobulins & their functions
IgA
IgD
IgE
IgM
IgG
Defends body surfaces “mucosa”
uncertain
Associated with allergies
Recognizes current blood antigens
Recognizes pathogens encountered in one’s past

12. Shapes of different Immunoglobulins
IgG
We’ll look more at these

14. Overview of B cells to Antibodies

15. IgG attacking a bacteria followed by macrophage “feeding”
antibody
Goodbye bacteria!
Macrophage
Bacteria
IgG

16. Vaccinations
Passive
Active

17. How fast do we produce IgG antibodies?

18. Immune Benefits of Breast Feeding
IgA’s

19. Onto the second type of lymphocyte known as the “T” lymphocyte…

20. T cells (CD4) Cytotoxic T cells (CD8) Helper T cells Memory T cells
thymus
T cells
(CD4) Cytotoxic T cells
(CD8) Helper T cells
Memory T cells
Suppressor T cells

21. The next part gets tricky

22. All T cells require cell to cell contact

24. http://highered. mcgraw-hill

25. Allergies and IGE’s

26. Allergies
IgE