1. What does this protein make up or do?
Chapter 13: Chromosome: 13
Name of Gene
Chromosome
DNA Sequence 13
RB1
Name of Protein
178,144 bp
retinoblastoma 1
transcription
What does this protein make up or do?
regulates cell growth and keeps cells from dividing too fast
Amino Acid Sequence
928 aa
translation
Condition/Disease
Retinoblastoma

2. Description of Retinoblastoma
Symptoms & Characteristics
Retinoblastoma is a rare type of eye cancer that usually develops in early childhood, typically before the age of 5
This form of cancer develops in the retina
The disease affects only one eye
When retinoblastoma is associated with a gene mutation that occurs in all of the body's cells

3. Description of Retinoblastoma
Who is affected?
Retinoblastoma most commonly affects young children, but can rarely occur in adults.
Outlook or quality of life:
Doctors do their best to preserves the child vision.
Without treatment, tumor will develop.
Treatments include medicine, such as Chemotherapy.
Doctors can also perform laser treatment or surgery.
Researcher: SD

4. References
"Retinoblastoma." Definition. Mayo Foundation, 17 Nov Web. 01 Mar Available at URL:
"Chromosome 13 (human)." Wikipedia. Wikimedia Foundation, 12 Mar Web. 04 Mar Available at URL:
"Chromosome 13." Genetics Home Reference. Genetics Home Reference, July Web. 02 Mar Available at URL: