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What Is the Role of Dual LAMA/LABA Bronchodilation in COPD Therapy in Light of New Clinical Data?

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Presentation on theme: "What Is the Role of Dual LAMA/LABA Bronchodilation in COPD Therapy in Light of New Clinical Data?"— Presentation transcript:

1 What Is the Role of Dual LAMA/LABA Bronchodilation in COPD Therapy in Light of New Clinical Data?

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3 Program Overview

4 Managing Stable COPD: Goals of Therapy

5 Updated GOLD Recommendations: First-line Pharmacologic Therapy for Stable COPD

6 Real-Life ICS Use in COPD: Adherence to Guidelines in France

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10 Available and Emerging LABA and LAMA Bronchodilators for COPD

11 β2-Agonists and Muscarinic Antagonists in COPD: Sites of Action

12 Effect of Indacaterol vs Blinded Tiotropium on Trough FEV1: INTENSITY

13 Single Dose of Umeclidinium/Vilanterol vs Single-Agent Components or Placebo

14 Considerations When Switching or Stepping Up Therapy

15 Health Status and Symptoms for Tiotropium + Olodaterol vs Monocomponents

16 Annualized Rate of Moderate or Severe Exacerbations: SPARK

17 Lung Function Improvement With Umeclidinium/Vilanterol vs Fluticasone/Salmeterol

18 Effect of ICS on Preventing COPD Exacerbations

19 Use of ICS and Risk for Pneumonia: Dose-Response Relationship

20 Real-World Management for COPD Population in the United Kingdom

21 ICS Withdrawal and Exacerbations in Patients With Severe COPD: WISDOM

22 Time to First Moderate or Severe COPD Exacerbation for Indacaterol/Glycopyrronium vs Salmeterol/Fluticasone

23 Improvements in SGRQ Score for Salmeterol/Fluticasone With or Without Glycopyrronium or Tiotropium

24 A PCP Approach to Monotherapy for COPD

25 A Pulmonologist’s View of COPD Treatment

26 Move Towards Phenotype-Directed Treatment?

27 Take-Home Messages

28 Take-Home Messages (cont)

29 Abbreviations

30 Abbreviations

31 References

32 References (cont)

33 References (cont)

34 References (cont)

35 References (cont)


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