1. Treatment of Complicated Intra-abdominal Infections

3. What Makes a cIAI Complicated?

4. Case: 72-Year-Old Woman Presented to Emergency Department Severely Ill

5. Burden of cIAIs on the Healthcare System

6. Epidemiology of cIAIs Community-acquired vs Hospital-associated

7. Common Pathogens in Community-acquired cIAIs*

8. Common Pathogens in Community-acquired cIAIs (cont)

9. cIAIs Polymicrobial

10. cIAIs Initial Evaluation and Management

11. cIAIs Initial Evaluation and Management (cont)

12. cIAIs Initial Evaluation and Management (cont)

13. Empiric Antibiotic Therapy for cIAIs

14. STOP IT Appropriate Duration of Antibiotic Therapy?

15. STOP IT Benefit of Antibiotics Limited to First Few Days After Intervention

16. Empiric Antibiotic Therapy for cIAI Severity-based Selection*

17. ESBLs

18. Antibiotic Resistance

19. Novel Cephalosporins Coupled With a Beta-lactamase Inhibitor

20. RECLAIM-1 and RECLAIM-2 Phase 3 Trial Results of the Single-pooled Dataset

21. ASPECT-cIAI A Randomized, Double-blind, Phase 3 Trial of Hospitalized Patients With cIAI

22. Novel Cephalosporins Coupled With a Beta-lactamase Inhibitor Main Targets of Therapy

23. Treatment Failure

24. Abbreviations