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FoxD3 Is a Novel, Epigenetically Regulated Tumor Suppressor in Gastric Carcinogenesis
Corina A. Schmid, Anne Müller Gastroenterology Volume 144, Issue 1, Pages (January 2013) DOI: /j.gastro Copyright © 2013 AGA Institute Terms and Conditions
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Figure 1 Epigenetic regulation of Helicobacter pylori-associated gastric cancer and its precursor lesions. Genes that are known to become hypermethylated at any stage of the gastric carcinogenesis sequence are annotated along with the biological process in which they function, if known. Gastric cancer of the intestinal type is believed to arise from Helicobacter-induced chronic gastritis that progresses via atrophic gastritis and intestinal metaplasia to in situ and, ultimately, invasive carcinoma. See text for details. Gastroenterology , 22-25DOI: ( /j.gastro ) Copyright © 2013 AGA Institute Terms and Conditions
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