1. Modulation of embryonic stem cell fate and somatic cell reprogramming by small molecules 
Xiu-Zhen Zhang 
Reproductive BioMedicine Online 
Volume 21, Issue 1, Pages (July 2010)
DOI: /j.rbmo
Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

2. Figure 1
The schematic illustration of somatic cell reprogramming to induced pluripotent stem cells. Somatic cells are reprogrammed to induced pluripotent stem cells through viral or non-viral introduction of exogenous transcription factors or protein transduction. Small molecules can improve reprogramming efficiency and replace certain transcription factors through epigenetic modifications or signalling pathway regulation. 5-AzaC=5-azacytidine; EBNA1=Epstein–Barr nuclear antigen-1; IPS=induced pluripotent stem; SAHA=suberoylanilide hydroxamic acid; TSA=trichostatin A; VPA=valproic acid.
Reproductive BioMedicine Online  , 26-36DOI: ( /j.rbmo )
Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions