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Figure 4 Pharmacodynamic comparison of crushed versus integral
tablets of P2Y12-receptor inhibitors in ST-segment elevation myocardial infarction Figure 4 | Pharmacodynamic comparison of crushed versus integral tablets of P2Y12-receptor inhibitors in ST-segment elevation myocardial infarction. a | Comparison in P2Y12 reaction units (PRU) measured by VerifyNow P2Y12 between crushed and whole tablets of 60 mg prasugrel loading dose. b | Comparison in PRU between crushed and whole tablets of 180 mg ticagrelor loading dose. ANOVA P values are for the comparison between groups over time. Reprinted from Sardella, G., Calcagno, S. & Mancone, M. Different prasugrel administration in STEMI patients: go faster and no fear to crush! J. Am. Coll. Cardiol. 67 (17), 2005–2007 © (2016), with permission from Elsevier. Reprinted from Sardella, G., Calcagno, S. & Mancone, M. Different prasugrel administration in STEMI patients: go faster and no fear to crush! J. Am. Coll. Cardiol. 67 (17), 2005–2007 © (2016), with permission from Elsevier Franchi, F. et al. (2017) Antithrombotic therapy for patients with STEMI undergoing primary PCI Nat. Rev. Cardiol. doi: /nrcardio
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