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The Impact of Freeze-Thaw Cycles on Epinephrine

Published byVera Shinta Pranoto Modified over 6 years ago

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Presentation on theme: "The Impact of Freeze-Thaw Cycles on Epinephrine"— Presentation transcript:

1 The Impact of Freeze-Thaw Cycles on Epinephrine
Heather Beasley, BS, Pearlly Ng, MD, Albert Wheeler, MD, William R. Smith, MD, Scott E. McIntosh, MD, MPH  Wilderness & Environmental Medicine  Volume 26, Issue 4, Pages (December 2015) DOI: /j.wem Copyright © 2015 Wilderness Medical Society Terms and Conditions

2 Figure 1 EpiPen autoinjector that has been disassembled to show internal ampule. Solution has been removed. Wilderness & Environmental Medicine  , DOI: ( /j.wem ) Copyright © 2015 Wilderness Medical Society Terms and Conditions

3 Figure 2 Degradation reactions of l-epinephrine. Adrenochrome creates a colored precipitate within epinephrine solutions. Discoloration of EpiPens indicates degradation has occurred and the autoinjector should be discarded. Wilderness & Environmental Medicine  , DOI: ( /j.wem ) Copyright © 2015 Wilderness Medical Society Terms and Conditions

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