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Volume 132, Issue 3, Pages 1180-1183 (March 2007)
Hepatitis B Virus X Protein and Pin1 in Liver Cancer: “Les Liaisons Dangereuses” Matias A. Avila, Kun P. Lu Gastroenterology Volume 132, Issue 3, Pages (March 2007) DOI: /j.gastro Copyright © 2007 AGA Institute Terms and Conditions
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Figure 1 The interaction and presumably isomerization (inset) of Ser-phosphorylated HBV X-protein (HBx) by the prolyl isomerase Pin1 increases the half-life of the viral protein. This results in the synergistic increase in the expression of HBx-target genes involved in HCC cell growth, survival, and tumorigenic potential. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2007 AGA Institute Terms and Conditions
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