Presentation is loading. Please wait.

Presentation is loading. Please wait.

Current Results and Future Research Priorities in Late Effects after Hematopoietic Stem Cell Transplantation for Children with Sickle Cell Disease and.

Similar presentations


Presentation on theme: "Current Results and Future Research Priorities in Late Effects after Hematopoietic Stem Cell Transplantation for Children with Sickle Cell Disease and."— Presentation transcript:

1 Current Results and Future Research Priorities in Late Effects after Hematopoietic Stem Cell Transplantation for Children with Sickle Cell Disease and Thalassemia: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric Hematopoietic Stem Cell Transplantation  Shalini Shenoy, Emanuele Angelucci, Staci D. Arnold, K. Scott Baker, Monica Bhatia, Dorine Bresters, Andrew C. Dietz, Josu De La Fuente, Christine Duncan, Javid Gaziev, Allison A. King, Michael A. Pulsipher, Angela R. Smith, Mark C. Walters  Biology of Blood and Marrow Transplantation  Volume 23, Issue 4, Pages (April 2017) DOI: /j.bbmt Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Mechanism of iron-related tissue injury in thalassemia patients. At transferrin saturation levels > 60% to 70%, levels of nontransferrin-bound serum iron (NTBI) and labile plasma iron (LPI) increase, resulting in iron-related damage to the liver, heart, bone marrow, and bones in situations of chronic iron overload after chronic transfusion therapy for thalassemia. (Modified from Angelucci and Pilo [60]). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions


Download ppt "Current Results and Future Research Priorities in Late Effects after Hematopoietic Stem Cell Transplantation for Children with Sickle Cell Disease and."

Similar presentations


Ads by Google