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SURVEY OF BIOCHEMISTRY Fatty Acid Oxidation
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Overview of Lipid Metabolism
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Triglyceride Breakdown
Triglycerides break down into 3 fatty acids and one molecule of glycerol.
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Activation of Fatty Acids Acyl-CoA Synthetase
Step 1
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Activation of Fatty Acids Acyl-CoA Synthetase
Step 2
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Carnitine as a Carrier
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Carnitine as a Carrier
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Fatty Acid Oxidation Saturated Fatty Acyl-CoA
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Fatty Acid Oxidation Step 2
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Fatty Acid Oxidation Step 3
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Fatty Acid Oxidation Step 4
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Examples of Unsaturated Fatty Acids
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Oxidation of Unsaturated Fatty Acids
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Oxidation of Unsaturated Fatty Acids
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Oxidation of Unsaturated Fatty Acids
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Oxidation of Unsaturated Fatty Acids
Moves the double bond!
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Another Problem in Oxidizing Unsaturated Fatty Acids
Poor substrate for enoyl-CoA hydratase
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Alternative Pathway for Unsaturated Fatty Acids
Study Figure and Figure 20-15
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Odd-Chain Fatty Acids
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