1. Essential to Life
ENZYMES

2. CharactericASE of Enzymes
“Traffic Cops” that keep everything
regulated (homeostasis)
Chemically specific
CATALYST : the rate of reactions by
a million

4. How do enzymes work?
Enzymes lower the amount of energy needed to reach the Activation Energy (Ea)
Ea must be reached for any chemical reaction to occur
Usually by kinetic energy
Ea= faster reaction

6. Mechanism of
Enzyme Action

7. Animation

8. Enzyme Action Mechanism
Let’s review:
-Substrate?
-Active Site?
-Induced-fit Model=Dan Koshland
Substrate binding causes structural change yielding a perfect fit.
- E + S E-S P + E

9. Enzyme on the Job
Hexokinase and Glucose

10. CharactericASE of Enzymes
Some enzymes are inactive until needed (digestive enzymes)
Others are deactivated immediately after use (blood clotting)
Reused
Examples

11. Ground Rules for Success!
Enzymes require stable pH to perform +/- 7 (pepsin is an exception)
Maintained body temperature or else…….

12. Denatured!!

13. 1. Animation on ENZYMES 2. Enzymes 3.Smartboard Presentation