1. Central pancreatectomy – a suitable surgical procedure for pancreatic metastases of other neoplasms?
Traian Dumitrascu
Andra Scarlat, Mihnea Ionescu, Irinel Popescu
Center of General Surgery and Liver Transplantation
Fundeni Clinical Institute
Bucharest, Romania

2. Introduction
Isolated pancreatic metastases of other neoplasms represent an uncommon pathology.
Standard pancreatic resections represent the current approach for patients with resectable disease.
However, the role of parenchyma-sparing pancreatectomies for such pathology is poorly investigated.
Reddy S et al, Lancet Oncol, 2009; Adler H et al, EJSO, 2014

3. Introduction
Central pancreatectomy is a parenchyma-sparing alternative resection to distal pancreatectomy, for benign and low malignant potential tumors located on the pancreatic isthmus and/ or body.
Iacono C et al, Br J Surg, 2013; Dumitrascu T et al, J Transl Med Res, 2015

5. Introduction

6. Aim of the study
To assess the oncological outcomes after central pancreatectomies for pancreatic metastases of other neoplasms.

7. Patients & Methods
A literature search was performed in order to identify and extract the data of the patients with central pancreatectomies for pancreatic metastases of other neoplasms.
The Kaplan-Meier curve was used to assess the long-term survival.

8. Results

9. Results Overall survival time 46 months
Dumitrascu T et al, Chirurgia, 2008

10. Results Overall survival time 28 months
Dumitrascu T et al, J Transl Med Res, 2015

11. Results Mean survival time = 99 months Central pancreatectomies for
pancreatic metastases of other neoplasms
Overall survival
Mean survival time = 99 months

12. Crippa S et al, World J Surg, 2006; Reddy S et al, Lancet Oncol, 2009;
Strobel (2009) %
Crippa
Crippa S et al, World J Surg, 2006; Reddy S et al, Lancet Oncol, 2009;
Strobel O et al, Ann Surg Oncol, 2009

13. Kwak JH et al, Korean J Hepatobiliary Pancreat Surg, 2014

14. Bassi C et al, Br J Surg, 2003

15. Conclusion
Although exceptionally performed, a central pancreatectomy appears to be an oncologically safe surgical procedure in selected patients with pancreatic metastases of other neoplasms of the pancreatic body and isthmus, with potentially better postoperative functional results.