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Modes of Inheritance
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A Summary of Mendel's Principles
Genes are passed from parents to their offspring. If two or more forms (alleles) of the gene for a single trait exist, some forms of the gene may be dominant and others may be recessive.
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In most sexually reproducing organisms, each adult has two copies of each gene. These genes are segregated (separated) from each other when gametes are formed. The alleles for different genes usually segregate independently of one another.
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Beyond Dominant and Recessive Alleles
Some alleles are neither dominant nor recessive, and many traits are controlled by multiple alleles or multiple genes.
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Incomplete Dominance When one allele is not completely dominant over another it is called incomplete dominance. In incomplete dominance, the heterozygous phenotype is a blend between the two homozygous phenotypes.
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RR A cross between red (RR) and white (WW) four o’clock plants produces pink-colored flowers (RW). WW Some alleles are neither dominant nor recessive. In four o’clock plants, for example, the alleles for red and white flowers show incomplete dominance. Heterozygous (RW) plants have pink flowers—a mix of red and white coloring.
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Codominance In codominance, both alleles contribute to the phenotype. In certain varieties of chicken, the allele for black feathers is codominant with the allele for white feathers. Heterozygous chickens are speckled with both black and white feathers. The black and white colors do not blend to form a new color, but appear separately.
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Heterochromatic eyes are codominant
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Rh Factors and blood typing reference
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Multiple Alleles Genes that are controlled by more than two alleles are said to have multiple alleles. An individual can’t have more than two alleles. However, more than two possible alleles can exist in a population. Blood type is determined by a single gene that has at least three different alleles A rabbit's coat color is determined by a single gene that has at least four different alleles.
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Different combinations of alleles result in the colors shown here.
KEY C = full color; dominant to all other alleles cch = chinchilla; partial defect in pigmentation; dominant to ch and c alleles ch = Himalayan; color in certain parts of the body; dominant to c allele c = albino; no color; recessive to all other alleles Coat color in rabbits is determined by a single gene that has at least four different alleles. Different combinations of alleles result in the four colors you see here. photo credits: 1. ©John Gerlach/Visuals Unlimited 2.Animals Animals/©Richard Kolar 3. ©Jane Burton/Bruce Coleman, Inc. 4. ©Hans Reinhard/Bruce Coleman, Inc. AIbino: cc Himalayan: chc, or chch Full color: CC, Ccch, Cch, or Cc Chinchilla: cchch, cchcch, or cchc
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What is Sex Linkage? In addition to their role in determining sex, the sex chromosomes have genes for many characters. Genes located on a sex chromosome are called sex linked genes. In humans the term usually refers to X-linked characters: genes located only on X chromosomes. Fathers can pass X-linked alleles to their daughters, but not sons. Mothers can pass sex-linked alleles to both sons and daughters.
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Red-green color blindness
X chromosome has a locus for color vision with two alleles: XN = Normal color vision Xn = Red-green color blindness Y chromosome does not have a color vision locus. If a male receives the Xn allele he will have impaired color vision (Xn Y), whereas a female with XNXn will not.
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Red-green color blindness
Parental Phenotypes Carrier Female x Normal Male Genotypes XNXn XNY Gametes XN Xn XN Y Female Gametes XN Xn Male Gametes XN XN XN Xn Y XN Y Xn Y Phenotypes Normal Female : Carrier Female : Normal Male : Color blind Male : : :
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COLORBLINDNESS
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HEMOPHILIA
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HEMOPHILIA
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HEMOPHILIA
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MUSCULAR DYSTROPHY
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MUSCULAR DYSTROPHY
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HUMAN BALDNESS
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HUMAN BALDNESS
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Beyond Dominant and Recessive Alleles
Polygenic Traits Traits controlled by two or more genes are said to be polygenic traits. Skin color in humans is a polygenic trait controlled by more than four different genes.
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