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Monitoring By Chromosome Banding Analysis (CBA) and FISH Of Circulating CD34+ Cells In Low-Risk MDS Patients Treated In The Le-Mon-5 Study With Lenalidomide.

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Presentation on theme: "Monitoring By Chromosome Banding Analysis (CBA) and FISH Of Circulating CD34+ Cells In Low-Risk MDS Patients Treated In The Le-Mon-5 Study With Lenalidomide."— Presentation transcript:

1 Monitoring By Chromosome Banding Analysis (CBA) and FISH Of Circulating CD34+ Cells In Low-Risk MDS Patients Treated In The Le-Mon-5 Study With Lenalidomide Monotherapy Reveals 82% Cytogenetic Responders With Different Response – , Evolutionary -, and Remission Patterns and No Increased Karyotype Evolution (KE)‏ by Katayoon Shirneshan, Uwe Platzbecker, Florian Nolte, Aristoteles Giagounidis, Katharina Götze, Richard F. Schlenk, Michael Lübbert, Gesine Bug, Friederike Braulke, Julie Schanz, and Ulrich Germing Blood Volume 122(21): November 15, 2013 ©2013 by American Society of Hematology

2 Median and standard deviation of del(5q) clone sizes during treatment with lenalidomide.
Katayoon Shirneshan et al. Blood 2013;122:2783 ©2013 by American Society of Hematology

3 Cytogenetic course in a patient with transient KE.
Katayoon Shirneshan et al. Blood 2013;122:2783 ©2013 by American Society of Hematology

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