Presentation is loading. Please wait.

Presentation is loading. Please wait.

Breaking Down Resistance

Published byGéraldine Pageau Modified over 6 years ago

Similar presentations

Presentation on theme: "Breaking Down Resistance"— Presentation transcript:

1 Breaking Down Resistance
Cell  Volume 159, Issue 3, (October 2014) DOI: /j.cell Copyright © Terms and Conditions

2 Unexpected signaling crosstalk underlies resistance to targeted therapy (Created by Caitlyn Webster; courtesy of Monique Dail and Kevin Shannon). Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

3 The tyrosine kinase inhibitor ponatinib (orange) binds to the ABL1T315I kinase domain (upper) but not ABLE255V/T315I (lower, point mutants in yellow) (Courtesy of Matthew Zabriskie and Nadeem Vellore). Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

Download ppt "Breaking Down Resistance"

Similar presentations

Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E Yumi Kim, Andrew J. Holland, Weijie Lan, Don W. Cleveland.

Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E Yumi Kim, Andrew J. Holland, Weijie Lan, Don W. Cleveland.
Waging War on Cancer with the Sword of Immunity Cell Volume 158, Issue 2, (July 2014) DOI: 10.1016/j.cell.2014.07.006 Copyright © 2014 Terms and Conditions.

Waging War on Cancer with the Sword of Immunity Cell Volume 158, Issue 2, (July 2014) DOI: /j.cell Copyright © 2014 Terms and Conditions.
SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration Amit R. Reddi, Valeria C. Culotta Cell Volume 152, Issue 1, Pages 224-235 (January.

SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration Amit R. Reddi, Valeria C. Culotta Cell Volume 152, Issue 1, Pages (January.
Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages 241-253 (March 2014) DOI: 10.1016/j.cell.2014.02.012 Copyright.

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.
What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages 20-44 (January 2014) DOI: 10.1016/j.cell.2013.12.012.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell
Common Sense about Taste: From Mammals to Insects David A. Yarmolinsky, Charles S. Zuker, Nicholas J.P. Ryba Cell Volume 139, Issue 2, Pages 234-244 (October.

Common Sense about Taste: From Mammals to Insects David A. Yarmolinsky, Charles S. Zuker, Nicholas J.P. Ryba Cell Volume 139, Issue 2, Pages (October.
Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages 38-52 (April 2008) DOI: 10.1016/j.cell.2008.03.011.

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell
Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: 10.1016/j.cell.2012.01.031 Copyright © 2012 Terms and Conditions Terms and Conditions.

Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.
Structurally Distinct Ca2+ Signaling Domains of Sperm Flagella Orchestrate Tyrosine Phosphorylation and Motility Jean-Ju Chung, Sang-Hee Shim, Robert A.

Structurally Distinct Ca2+ Signaling Domains of Sperm Flagella Orchestrate Tyrosine Phosphorylation and Motility Jean-Ju Chung, Sang-Hee Shim, Robert A.
The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: 10.1016/j.cell.2011.12.011 Copyright © 2011 Terms and Conditions Terms and Conditions.

The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.
WHAMM Is an Arp2/3 Complex Activator That Binds Microtubules and Functions in ER to Golgi Transport Kenneth G. Campellone, Neil J. Webb, Elizabeth A. Znameroski,

WHAMM Is an Arp2/3 Complex Activator That Binds Microtubules and Functions in ER to Golgi Transport Kenneth G. Campellone, Neil J. Webb, Elizabeth A. Znameroski,
The Coming Peptide Tidal Wave

The Coming Peptide Tidal Wave
Inhibitor of MAP kinase activation blocks colon cancer growth

Inhibitor of MAP kinase activation blocks colon cancer growth
Virology Select Cell Volume 141, Issue 2, (April 2010)

Virology Select Cell Volume 141, Issue 2, (April 2010)
Clinical Application of Therapies Targeting VEGF

Clinical Application of Therapies Targeting VEGF
Another Piece of the p27Kip1 Puzzle

Another Piece of the p27Kip1 Puzzle
c-Kit as a Novel Potential Therapeutic Target in Colorectal Cancer

c-Kit as a Novel Potential Therapeutic Target in Colorectal Cancer
Unweaving the Autism Spectrum

Unweaving the Autism Spectrum
Genomics: Think Global, Act Local

Genomics: Think Global, Act Local
C2 Can Do It, Too Cell Volume 121, Issue 2, Pages (April 2005)

C2 Can Do It, Too Cell Volume 121, Issue 2, Pages (April 2005)

Similar presentations

Ads by Google