1. Survival Outcomes at 3 Years
Pre-Imatinib
With Imatinib
Total With Imatinib
Part 1 Late Imatinib
Part 2 Early Imatinib
% OS (95% CI)
25 (20–30)
43 (34–49)
34 (24–44)
48 (36–60)
P=0.0001**
P=0.05^
% EFS (95% CI)
19 (14–24)
37 (29–44)
29 (19–38)
35 (34–56)
P<0.0001**
P=0.04^
% RFS (95% CI)
36 (28–43)
53 (45–63)
45 (33–57)
62 (50–75)
P= **
P=0.02^
EFS=event free survival; OS=overall survival; RFS=relapse free survival
P values are for two comparisons: ** denotes the comparison between patients receiving any Imatinib and patients receiving none and ^ denotes the comparison between the Early and Late Imatinib cohorts
169