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Clinical Nutrition Experimental

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Presentation on theme: "Clinical Nutrition Experimental"— Presentation transcript:

1 Clinical Nutrition Experimental
Effects of short-term fasting on gut-associated lymphoid tissue and intestinal morphology in mice  Kazuya Higashizono, Kazuhiko Fukatsu, Ayako Watkins, Tomoki Watanabe, Midori Noguchi, Eiji Tominaga, Motonari Ri, Satoshi Murakoshi, Hiroshi Yasuhara, Yasuyuki Seto  Clinical Nutrition Experimental  Volume 18, Pages 6-14 (April 2018) DOI: /j.yclnex Copyright © 2018 The Authors Terms and Conditions

2 Fig. 1 Histological analysis. A: Histological features of the jejunum and ileum with HE staining. Marked mucosal atrophy was observed in the Fasted − water and Fasted + water groups. Original magnification: 100×. B: Villous height and crypt depth. Ten villi and crypts per section were evaluated. *P < 0.05 vs Control. Clinical Nutrition Experimental  , 6-14DOI: ( /j.yclnex ) Copyright © 2018 The Authors Terms and Conditions

3 Fig. 2 Mucosal Immunoglobulin A (IgA) levels in intestinal, nasal and bronchoalveolar. IgA levels in washings from the small intestinal lumen, nasal cavity and bronchoalveolar space were measured with ELISA. Values are means ± SE. SE: standard error. Clinical Nutrition Experimental  , 6-14DOI: ( /j.yclnex ) Copyright © 2018 The Authors Terms and Conditions

4 Fig. 3 GALT lymphocyte numbers in each group. Lymphocytes were isolated from Peyer's patches, intraepithelial spaces and the lamina propria of the remaining small intestine. Values are means ± SE. SE: standard error. *P < 0.05 vs. Control. Clinical Nutrition Experimental  , 6-14DOI: ( /j.yclnex ) Copyright © 2018 The Authors Terms and Conditions


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