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The V410I (G1228A) variant of the caspase-10 gene is a common polymorphism in the Danish population by Kirsten Grønbæk, Tine Dalby, Jesper Zeuthen, Elisabeth.

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Presentation on theme: "The V410I (G1228A) variant of the caspase-10 gene is a common polymorphism in the Danish population by Kirsten Grønbæk, Tine Dalby, Jesper Zeuthen, Elisabeth."— Presentation transcript:

1 The V410I (G1228A) variant of the caspase-10 gene is a common polymorphism in the Danish population
by Kirsten Grønbæk, Tine Dalby, Jesper Zeuthen, Elisabeth Ralfkiaer, and Per Guldberg Blood Volume 95(6): March 15, 2000 ©2000 by American Society of Hematology

2 Detection of the V410I (G1228A) variant of the caspase-10 gene in DNA from healthy blood donors.(A) Representative denaturing gradient gel electrophoresis (DGGE) analysis of a region encompassing nucleotides (codons ) of the caspase-10 gene. Detection of the V410I (G1228A) variant of the caspase-10 gene in DNA from healthy blood donors.(A) Representative denaturing gradient gel electrophoresis (DGGE) analysis of a region encompassing nucleotides (codons ) of the caspase-10 gene. (B) Direct sequence analysis of a sample with aberrant DGGE pattern, showing the G1228A variant. Kirsten Grønbæk et al. Blood 2000;95: ©2000 by American Society of Hematology


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