1. Co-prescription of Gastroprotective Agents and Their Efficacy in Elderly Patients Taking Nonsteroidal Anti-inflammatory Drugs: A Systematic Review of Observational Studies 
Stephanie Medlock, Saeid Eslami, Marjan Askari, Zhila Taherzadeh, Dedan Opondo, Sophia E. de Rooij, Ameen Abu-Hanna 
Clinical Gastroenterology and Hepatology 
Volume 11, Issue 10, Pages e10 (October 2013)
DOI: /j.cgh
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2. Figure 1 Search flow diagram. GPA, gastroprotective agent.
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3. Figure 2
Reported rates of co-prescription for patients 65 years and older. Each point represents the rate of co-prescription reported for patients 65 and older in each study. The point is placed at the middle year of the study, with the line extending to show the years in which the study took place. Larger studies are represented with a larger point (smallest <1000 patients, largest >100,000 patients).
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4. Figure 3
Unadjusted results from observational studies of efficacy of gastroprotective agents in elderly patients. A forest plot is shown for unadjusted results of the 5 studies reporting numbers of patients taking NSAIDs who had a GI event with and without PPIs (Mantel-Haenszel [M-H] OR, random effects model). The studies were highly heterogeneous (I2 = 97%), as indicated by minimal overlap of CIs in the graph; thus, the cumulative result is not considered reliable and is not shown. Number of events for van Leen et al36 were estimated from information given in the study.
Clinical Gastroenterology and Hepatology  , e10DOI: ( /j.cgh )
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5. Supplementary Figure 1
Funnel plot of unadjusted results of the 5 studies that reported on the number of GI events in patients with and without gastroprotective agents. A funnel plot is not considered reliable with fewer than 10 studies; therefore these results are given for reference only.
Clinical Gastroenterology and Hepatology  , e10DOI: ( /j.cgh )
Copyright © 2013 AGA Institute Terms and Conditions