1. Nintedanib Dose Modifications
Filming: 15th of Febuary 2016, London, UK
Prof. Vincent Cottin
Prof. Luca Richeldi

2. Nintedanib was effective even in patients with dose reductions and treatment interruptions
Change from baseline in FVC in patients treated with nintedanib1
≥1 dose reduction due to side effects
≥1 treatment interruption due to side effects
These results indicate that the dosing regimen used in the INPULSIS® trials, which allowed for dose reductions and treatment interruptions to manage adverse events, was effective in patients with IPF.
Yes (n=178)
No (n=460)
Yes (n=151)
No (n=487)
Absolute mean change from baseline in FVC (mL)
1. Richeldi L, et al. Poster presented at PFF Summit 2015.
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