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Transport Across Membranes
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Importance of Transport
intake of nutrients removal of wastes communication with environment & other cells blocking entry of harmful substances Cell membrane is selectively permeable.
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Passive Transport the movement of materials across the cell membrane without the use of chemical energy (ATP) movement is due to diffusion
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Diffusion the net movement of a substance from an area of higher to an area of lower concentration until a state of dynamic equilibrium Image from:
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Simple Diffusion substances move unassisted
small non-polar molecules, small uncharged polar molecules larger molecules & ions need assistance Image from: small non-polar molecules (O2, CO2, steroid hormones, some drugs) and small polar molecules (H2O, glycerol)
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Facilitated Diffusion
diffusion across membrane assisted by integral membrane proteins called transport proteins channel proteins form hydrophilic pathways for water & ions; ion channels are usually voltage-gated carrier proteins usually have specificity
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Facililated Diffusion
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Carrier Proteins Image from:
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Osmosis the diffusion of water across a membrane
water follows concentration gradient until equilibrium
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Osmosis direction of osmosis changes depending on type of solution surrounding the cell: isotonic solution hypotonic solution hypertonic solution
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Cell in Isotonic Solution
The Plasma Membrane 11/24/2018 Cell in Isotonic Solution 10% NaCL 90% H2O ENVIRONMENT CELL NO NET MOVEMENT 10% NaCL 90% H2O What is the direction of water movement? equilibrium The cell is at _______________. 11 G. Podgorski, Biol. 1010 11
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Cell in Hypotonic Solution
The Plasma Membrane 11/24/2018 Cell in Hypotonic Solution 10% NaCL 90% H2O CELL 20% NaCL 80% H2O What is the direction of water movement? 12 G. Podgorski, Biol. 1010 12
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Cell in Hypertonic Solution
The Plasma Membrane 11/24/2018 Cell in Hypertonic Solution 15% NaCL 85% H2O ENVIRONMENT CELL 5% NaCL 95% H2O What is the direction of water movement? 13 G. Podgorski, Biol. 1010 13
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Animal Cells Prefer Isotonic Environments
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Red Blood Cells Image from:
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Plant Cells Prefer Hypotonic Environments
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Active Transport Image from:
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Active Transport the movement of materials against the concentration gradient (from low to high concentrations) requires cellular energy (ATP)
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Primary Active Transport
pumps move positively charged ions (H+, Ca2+, Na+, K+) across membranes creates electrochemical gradient Image from:
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Secondary Active Transport
uses gradient established by a primary active transport pump Image from:
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Bulk Transport movement of larger substances across a cellular membrane requires energy (ATP) exocytosis & endocytosis
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Endocytosis Image from:
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Exocytosis Neurotransmitters
Image from: Neurotransmitters
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