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Addressing Iron Deficiency in Chronic HF
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Introduction
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Prevalence of ID in Patients With HF
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Prevalence of ID in Patients With HF (cont)
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Importance of Iron for Functioning and Survival
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Prevalence of ID According to NYHA FC
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Etiology of ID in HF
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Definition of ID
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Blood Tests Used to Diagnose ID
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Definition of ID (cont)
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Screening for ID in Patients With HF
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Symptoms of ID in Patients With HF
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FCM: Summary of Clinical Evidence
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Oral Iron Supplementation
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High-Dose Oral Iron in HFrEF: Results of the IRONOUT HF Trial
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Lack of Efficacy of Oral Iron in IRONOUT HF Study: One Explanation
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Detrimental Effects of ID
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FERRIC-HF II Study
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Efficacy of FCM Stratified According to the Presence of Anemia
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CONFIRM-HF: Time to First Hospitalization Due to Worsening HF
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Effect of FCM on Patient Outcomes: An Individual Patient Data Meta-Analysis
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CVOTs in Patients Treated With FCM
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Prevalence of Anemia, ID, and ID Anemia in Renal Transplant Recipients
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Impact of FCM on Renal Function: The FAIR-HF Study
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Overall FCM Is Safe and Well Tolerated
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FCM: Safety and Tolerability
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FCM: Safety and Tolerability (cont)
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FCM: Safety and Tolerability (cont)
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Replenishing Iron Stores: Monitoring and Follow-Up
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Iron Replacement in Patients With HFpEF
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FAIR-HFpEF
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Management of ID in Patients With HF: Practical Considerations
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Management of ID in Patients With HF: Practical Considerations (cont)
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Absolute ID
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Evaluation of ID in Patients With HF
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Management of ID in Patients With HF: A Multidisciplinary Team Approach
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Summary and Conclusions
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Abbreviations
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Abbreviations (cont)
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