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Published byJemima Charles Modified over 6 years ago
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The detection of microbial DNA but not cultured bacteria is associated with increased mortality in patients with suspected sepsis—a prospective multi-centre European observational study M.J. O’Dwyer, M.H. Starczewska, J. Schrenzel, K. Zacharowski, D.J. Ecker, R. Sampath, D. Brealey, M. Singer, N. Libert, M. Wilks, J.-L. Vincent Clinical Microbiology and Infection Volume 23, Issue 3, Pages 208.e1-208.e6 (March 2017) DOI: /j.cmi Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions
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Fig. 1 Twenty-eight-day mortality. Among those patients with a negative blood culture result, those with a positive PCR/ESI-MS test result have a higher mortality. A McNemar’s test was performed on the non-surviving patients, which indicated that the total number of positive tests for each method was statistically different (McNemar test statistic=45, degree of freedom=1 and p <0.0001). BC, blood culture; PCR/ESI-MS, PCR followed by electrospray ionization-mass spectrometry. Clinical Microbiology and Infection , 208.e1-208.e6DOI: ( /j.cmi ) Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions
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