2. Program Goal

3. Current Stroke Guidelines: AHA/ASA

4. Current Stroke Guidelines: National Quality Forum

5. Current Stroke Guidelines: ACEP/ANA

6. Evolution of Data on Use of Thrombolytic Therapy

7. Evolution of Data: Meta-analyses

8. Evolution of Data: Meta-analyses (cont)

9. Evolution of Data (cont)

10. Controversies of tPA Therapy

11. Controversies of tPA Therapy (cont): Observational Data

12. Controversies of tPA Therapy (cont): Bias

13. Controversies of tPA Therapy (cont): Malpractice

14. AHA Get With the Guidelines-Stroke Data: Improved Door-to-Needle Times

15. AHA Get With the Guidelines-Stroke Data: Outcomes

16. Summary and Key Points

17. Abbreviations

18. References

19. References (cont)

20. References (cont)

21. References (cont)