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Anterior = Adenophypophysis
Posterior = Neurophypohysis
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Adenohypophysis --superior hypohphyseal artery--portal system in pars tuberalis—superior hypophyseal vein. Hypothalamic neurons release hormones into portal sytem. Pars Tuberalis
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Neurovascular hypothesis—secretions from hypothalamic neurons regulate pituitary secretion.
PVN and SON neurons synthesize hormones (oxytocin & vasopressin) that are released directly. Other nuclei secrete hormones that control the adenohypophysis (via portal system)
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Hyposecretion—hypothalamic disease, tumor
Hypersecretion—pituitary tumors, enhanced hypothalamic stimulation
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