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A randomized trial of assessment interventions to reduce drug use and HIV/STI sexual risk among young adults who use drugs in the club scene Steven P. Kurtz, Mance E. Buttram, Maria E. Pagano, and Hilary L. Surratt Lisbon Addictions Oct. 2017
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Support This research was supported by grant number DA from the National Institute on Drug Abuse. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute on Drug Abuse or the National Institutes of Health. There are no conflicts to report.
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Miami is an international center
of nightclub culture “Every night is like New Year’s Eve on South Beach, and drugs and sex are all part of it.”
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Club Drugs Illicit “club drugs” include: Ecstasy Cocaine
Methamphetamine LSD GHB “Designer” stimulants and hallucinogens
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Background Extensive polydrug use among nightclub attendees
Pervasive resistance to participation in formal interventions Efficacious interventions to reduce drug use and related consequences are not apparent.
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The South Beach study RCT of behavioral interventions to reduce substance use and HIV transmission risk among young adults.
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The South Beach study Study arms: 1) interviewer-administered (CAPI)
and 2) self-administered (ACASI) comprehensive health and social risk assessments 3) waitlist control
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OUTCOME MEASURES Primary Outcomes (past 90 days):
Club drug use frequency Risky vaginal/anal sex frequency Measured at baseline and 3-, 6- and 12-months post intervention.
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Hypothesis Participants randomized to the CAPI and ACASI intervention conditions will reduce their substance use and related behaviors more than those assigned to waitlist control.
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The South Beach study Eligibility criteria: Ages 18-39
Past 90 day behaviors Heterosexual sex Used “club drugs” at least 3 times Misused a scheduled Rx drug Attends large EDM clubs
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The South Beach study Respondent Driven Sampling N=750
Enrollment
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MEASURES Substance use abstinence frequency Substance dependence symptoms: DSM-IV items, including withdrawal symptoms and tolerance (range 1-7). Mental distress symptoms: DSM-IV items assessing past year anxiety, depression and somaticism (range 1-25).
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Analytical approach Intent to treat basis
Effect size estimates (Cohen’s d) Log-transformed measures
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Results a57 controls missing data (did not complete 12-month assessment)
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Results a57 controls missing data (did not complete 12-month assessment); bOne ACASI participant missing data.
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Results
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results
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results
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results
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LIMITATIONS Data are self reported
Eligibility criteria limit generalizability Diagnostics not clinician-administered
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Conclusions Hypothesis partially confirmed – CAPI was superior to control. Substance dependence and mental distress symptoms below clinically significant levels Contrary to the hypothesis – ACASI showed lower efficacy compared to control
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Conclusions Interpersonal interaction appears beneficial
Demonstrates efficacy of single session intervention Acceptable to target population No difference between CAPI – ACASI on ‘sensitive’ measures
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Steven P. Kurtz and Mance E. Buttram arsh.nova.edu
Thank you Steven P. Kurtz and Mance E. Buttram arsh.nova.edu
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