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Kenneth L. Scott, Scott Powers  Cancer Cell 

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1 Functionally Assessing Candidate Drivers Advances Precision Cancer Medicine 
Kenneth L. Scott, Scott Powers  Cancer Cell  Volume 30, Issue 2, Pages (August 2016) DOI: /j.ccell Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Approaches to Advancing Cancer Precision Medicine
There are three general approaches that all converge upon advancing cancer precision medicine. The first approach, which is highlighted by the Berger et al. study in this issue of Cancer Cell, is to functionally validate new oncogenic drivers. This approach, coupled with the second approach of linking driver alterations to the response to existing cancer therapeutics, feeds into the continually evolving next-generation sequencing (NGS) diagnostic tests. The third approach, equally important, is to develop therapeutics to oncogenic drivers that have not yet been successfully targeted. Cancer Cell  , DOI: ( /j.ccell ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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