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Volume 115, Issue 6, Pages (December 1998)

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Presentation on theme: "Volume 115, Issue 6, Pages (December 1998)"— Presentation transcript:

1 Volume 115, Issue 6, Pages 1381-1386 (December 1998)
Hypermethylation of the CDKN2/p16 promoter during neoplastic progression in Barrett's esophagus  Bodo Klump, Chih-Jen Hsieh, Karlheinz Holzmann, Michael Gregor, Rainer Porschen  Gastroenterology  Volume 115, Issue 6, Pages (December 1998) DOI: /S (98) Copyright © 1998 American Gastroenterological Association Terms and Conditions

2 Fig. 1 Gel showing in the first of each three lanes the PCR product for unmodified DNA (W), in the second lane the product of PCR specific for unmethylated templates (U), and in the third lane the product of PCR specific for methylated templates (M). The analysis of three specimens is demonstrated. IND, indefinite for dysplasia. Gastroenterology  , DOI: ( /S (98) ) Copyright © 1998 American Gastroenterological Association Terms and Conditions

3 Fig. 2 Rate of samples with detected p16 promoter hypermethylation relative to grade of dysplasia. NEG, no dysplasia; IND, histomorphological lesions indefinite for dysplasia; CA, adenocarcinoma. Gastroenterology  , DOI: ( /S (98) ) Copyright © 1998 American Gastroenterological Association Terms and Conditions


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