1. CH 23
Anatomy of
the Stomach
James F. Thompson, Ph.D.

2. Stomach “J” shaped enlargement of GI tract under diaphragm
Located between the esophagus and duodenum
Functions as a storage depot where much mechanical and some chemical digestion occurs

3. Stomach

4. Rugae
H. pylori
Gastric ulcer

5. General Histology of GI Tract
Same histological organization from inside to outside and from end to end

6. Rugae in Cross Section

7. Stomach Lining
Mucosa
Simple columnar epithelium with goblet cells and gastric pits
Gastric glands with secretory cells
chief cells
parietal cells
mucous cells
G cells (enteroendocrine) – secrete gastrin
Secretions: 2-3 L l day

8. Gastric Glands Mucosal Gastric Glands Intramural Gland  Submucosa
Muscularis

9. Fundus: gastric glands

10. G Cells Produce Gastrin

11. End CH 23 Anatomy of the Stomach