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Hatem Abu Hashim  Reproductive BioMedicine Online 

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1 Twenty years of ovulation induction with metformin for PCOS; what is the best available evidence? 
Hatem Abu Hashim  Reproductive BioMedicine Online  Volume 32, Issue 1, Pages (January 2016) DOI: /j.rbmo Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

2 Figure 1 Insulin resistance as a significant contributor to polycystic ovary syndrome Rotterdam diagnostic criteria. IGF-1 = Insulin growth factor-1; PCO = polycystic ovary; SHBG = sex hormone-binding-globulin. ↑ = Increase; ↓ = Decrease. Reproductive BioMedicine Online  , 44-53DOI: ( /j.rbmo ) Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

3 Figure 2 The study flow diagram.
Reproductive BioMedicine Online  , 44-53DOI: ( /j.rbmo ) Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

4 Figure 3 Evidence-based decision making for clomiphene-resistant infertile women with polycystic ovary syndrome. LOD, laparoscopic ovarian diathermy; PCOS, polycystic ovary syndrome. Reproductive BioMedicine Online  , 44-53DOI: ( /j.rbmo ) Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

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