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Figure 3 Pedigree of familial idiopathic transverse myelitis

Published byNigel Fleming Modified over 6 years ago

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Presentation on theme: "Figure 3 Pedigree of familial idiopathic transverse myelitis"— Presentation transcript:

1 Figure 3 Pedigree of familial idiopathic transverse myelitis
Pedigree of familial idiopathic transverse myelitis (A) Family with 2 affected sisters who are both positive for the VPS37A mutation (closed circles, P arrows) and 2 healthy brothers, one of whom is a carrier (half-filled square) and one of whom is not (clear square) and a healthy sister (clear circle). Their parents are not available to be tested. (B) A patient with idiopathic transverse myelitis was screened and found to have the mutation, with no known family history (closed circle, P arrow). Her sister is a healthy carrier (half-filled circle). Maureen A. Mealy et al. Neurol Genet 2018;4:e213 Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.

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Figure 1 Box plot of the venous diameter in lesions

Figure 1 Box plot of the venous diameter in lesions
Figure 2 Needle biopsy of the left vastus lateralis

Figure 2 Needle biopsy of the left vastus lateralis
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Figure 1 Stiff-person syndrome spectrum patient serum bound to membranes of live GlyRα1-transfected HEK293 cells Stiff-person syndrome spectrum patient.
Figure 2 Spinal cord lesions

Figure 2 Spinal cord lesions
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Figure 4 Correlation of age with [11C](R)-PK11195 binding in the normal-appearing white matter (NAWM) and thalami Correlation of age with [11C](R)-PK11195.

Figure 4 Correlation of age with [11C](R)-PK11195 binding in the normal-appearing white matter (NAWM) and thalami Correlation of age with [11C](R)-PK11195.
Figure 1 Coronal MRI images showing the evolution of white matter abnormality and atrophy of patient 1 Coronal MRI images showing the evolution of white.

Figure 1 Coronal MRI images showing the evolution of white matter abnormality and atrophy of patient 1 Coronal MRI images showing the evolution of white.
Figure 1 Hierarchical clustering (HCL) outcome of all tested samples with the expression profile of the case report set as unknown Hierarchical clustering.

Figure 1 Hierarchical clustering (HCL) outcome of all tested samples with the expression profile of the case report set as unknown Hierarchical clustering.
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Figure 1 Spine MRI, sagittal and axial views of patients with idiopathic transverse myelitis with VPS37A mutations Spine MRI, sagittal and axial views.
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Figure Pedigree of the family

Figure Pedigree of the family
Figure 3 Transcripts of the splicing mutation (c

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