1. Asthma, allergy, and responses to methyl donor supplements and nutrients 
Sunita Sharma, MD, MPH, Augusto Litonjua, MD, MPH 
Journal of Allergy and Clinical Immunology 
Volume 133, Issue 5, Pages (May 2014)
DOI: /j.jaci
Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2. Fig 1
Simplified diagram of the one-carbon metabolic pathway. The figure demonstrates where dietary methyl donors, identified in red, are involved in the one-carbon metabolic pathway and how they influence DNA methylation. DNA methylation depends on the availability of methyl groups from S-adenosyl-methionine, which is derived from methionine. This figure highlights the connection between folate, choline, methionine, betaine, and vitamins B2, B6, and B12 on DNA methylation. The pathways intersect at the formation of methionine from homocysteine.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions