1. Enzyme Structure and Function
Journal 3-4
Enzyme Structure and Function

2. Unit 1: Biochemistry and Digestion
Reactions in the body
Anabolic – building up
Example: Dehydration synthesis
Endergonic
Absorbs/requires energy
Energy-poor reactants  Energy-rich products
Catabolic – breaking down (CATastrophic…)
Example: Degradation Hydrolysis
Exergonic
Releases energy
Energy-rich reactants  Energy-poor products

3. Reading an energy graph
Unit 1: Biochemistry and Digestion
Reading an energy graph

4. What are Enzymes? Enzymes are proteins Biological Catalysts
There are as many as 2000 different enzymes in a single cell

5. What do enzymes do?
Speed up reactions (sometimes 10 billion times faster!)
Work by lowering activation energy

6. What do enzymes look like?
Enzymes are globular proteins
Tertiary or quandary structures (Protein folding)
Active site – reactive location on an enzyme

7. How do enzymes work? Enzyme and substrate are in the same area
Enzyme grabs substrate(s) into its active site
Substrate is changed into the product(s) of reaction
Enzyme releases product(s) and returns to its original shape to be used again

8. How do enzymes work?
Anabolic reactions:
Catabolic reactions:

9. Enzyme specificity Each enzyme has a specifically shaped active site
Only one substrate fits into the active site
Each enzyme only catalyzes one reaction

10. What affects enzyme function?
What might slow down enzymes?
Each enzyme requires specific conditions to function
Temperature
pH – amount of acid
Salinity – amount of salt
All of the above 3 can denature an enzyme
Enzyme concentration
Amount of enzyme