1. Lecture 17 Web: pollev.com/ucibio Text: To: 37607
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2. Glucose energy production

3. Anabolic roles of TCA

4. Funky cycles… Acetyl CoA Oxaloacetate Citrate Malate Amino acids, etc.
Fatty acids, etc.
Malate
Malate

5. Anaplerotic reactions

6. Compartmentalization
Glycolysis: Where is NADH produced?
Where is the ETC?

7. Moving NADH, 1: The Glycerol 3-PO4 shuttle

8. Moving NADH, 1: The Glycerol 3-PO4 shuttle

9. Moving NADH, 2: Malate-Asp shuttle

10. Moving NADH, 2: Malate-Asp shuttle

11. Moving others across mitochondria

12. How do we know about e- flow?
Can’t “label” electrons!
So, how to follow e- flow?

13. The ETC

14. Complex I

15. Complex II

16. Complex III

17. Complex IV

18. The ETC

19. The ETC

20. e- energy  Proton gradient
ETC
e- energy  Proton gradient
High energy e- from metabolism
Proton gradient  ATP?