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Published byMerryl Bradford Modified over 6 years ago
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For the Urologist by the Urologist: Essential Concepts in Managing mCRPC
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Goals
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Case Study: Newly Diagnosed Low Volume Metastatic Disease
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CHAARTED: Benefit of Docetaxel
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Toxicity Grade 3 AE or Greater
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Treating the Primary Tumor
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Case Study, Continued
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Abiraterone COU-AA-302 Trial
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Enzalutamide PREVAIL Trial
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Treatment Considerations: Use of Immunotherapy
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Sipuleucel-T
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Treatment Considerations: Abiraterone vs Enzalutamide
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Case Study: mCRPC Progressing Through Second Generation Androgen Axis Inhibitors
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Further Treatment Considerations
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Emerging Biomarkers
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Biomarkers: Mutations of DNA Repair and High Rate of Response to Olaparib
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Cabazitaxel
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Conclusions
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Remaining Questions
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