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Prashant Singh, Ananya Arora, Tor A. Strand, Daniel A

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1 Global Prevalence of Celiac Disease: Systematic Review and Meta-analysis 
Prashant Singh, Ananya Arora, Tor A. Strand, Daniel A. Leffler, Carlo Catassi, Peter H. Green, Ciaran P. Kelly, Vineet Ahuja, Govind K. Makharia  Clinical Gastroenterology and Hepatology  Volume 16, Issue 6, Pages e2 (June 2018) DOI: /j.cgh Copyright © 2018 AGA Institute Terms and Conditions

2 Figure 1 Forest plot of pooled global seroprevalence of celiac disease based on 96 studies using tTG and/or AEA. Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

3 Figure 2 Forest plot of pooled global prevalence of biopsy-proven celiac disease based on 57 studies. Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

4 Figure 3 Worldwide celiac disease seroprevalence rates for the countries reporting data. Prevalence values were stratified into 4 groups of percentiles representing the 0 to 25th percentile (light gray) to the 76th to 100th percentile (dark black). The lowest and highest percentiles include countries with pooled national prevalence ranging from 0.2% to 0.8% and 2.1% to 8.5%, respectively. Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

5 Figure 4 Worldwide celiac disease prevalence rates (based on biopsy) for the countries reporting data. Prevalence values were stratified into 4 groups of percentiles representing the 0 to 25th percentile (light gray) to the 76th to 100th percentile (dark black). The lowest and highest percentiles include countries with a pooled national prevalence ranging from 0.2% to 0.4% and 0.9% to 2.4%, respectively. Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

6 Supplementary Figure 1 Flow diagram of studies included in the present meta-analysis. Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions


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